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Urine Immunofixation. Urine immunofixation electrophoresis remains important and is complementary to serum free light chain. Monoclonal protein detection urine. Serum FLC concentrations required for producing BJ proteins detected by IFE were determined. Immunofixation electrophoresis of serum or urine is most often ordered to evaluate a monoclonal globulin detected in a protein electrophoresis or to delineate a possible lymphoproliferative process particularly myeloma.
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This protein may show up in both the serum and urine or it may only be seen in the urine. Immunofixation electrophoresis of serum or urine is most often ordered to evaluate a monoclonal globulin detected in a protein electrophoresis or to delineate a possible lymphoproliferative process particularly myeloma. Monoclonal protein detection urine. Urine IFE tests are often done if IFE blood test results were not normal. α 2 -globulin urine. However uIFE is not always performed for sIFE-negative patients.
Urine immunofixation is a test to look for abnormal proteins in urine.
Urine immunofixation is a test to look for abnormal proteins in urine. The lab treats the gel to keep only certain proteins. A stain makes different proteins show up as bands or peaks. Serum FLC concentrations required for producing BJ proteins detected by IFE were determined. Response criteria for multiple myeloma MM require monoclonal protein M-proteinnegative status on both serum immunofixation electrophoresis sIFE and urine uIFE immunofixation electrophoresis for classification of complete response CR. The primary reason protein and immunofixation electrophoresis are requested on urine is to look for monoclonal protein production.
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Different patterns between serum immunofixation electrophoresis SIFE and urine immunofixation electrophoresis UIFE happen occasionally and laboratorians should understand the mechanisms behind the differences and additional tests required for complicated cases. Immunofixation tests can also be done in urine. The lab treats the gel to keep only certain proteins. A stain makes different proteins show up as bands or peaks. Urine IFE tests are often done if IFE blood test results were not normal.
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